PCN11 PREVENTION OF OXALIPLATIN HYPERSENSITIVITY REACTION AND COST SAVING
نویسندگان
چکیده
منابع مشابه
Serious delayed hypersensitivity reaction to oxaliplatin.
With great interest we read the articles of Siu et al. [1] and Maindrault-Goebel et al. [2]. Both report on immediate type hypersensitivity reactions to oxaliplatin, occurring in about 10–15% of patients, mostly after several courses of therapy. We recently observed a quite different presentation of hypersensitivity to oxaliplatin, consisting of severe respiratory symptoms about 24 h after the ...
متن کاملHypersensitivity Reactions to oxaliplatin: incidence and management.
Oxaliplatin (Eloxatin) is a novel platinum compound that has activity in a wide variety of tumors. Several hypersensitivity reactions distinct from laryngopharyngeal dysesthesia have been described. We retrospectively analyzed 169 consecutive patients who received oxaliplatin for esophageal or colorectal cancer between 1/1/00 and 7/31/02 and reviewed any significant adverse reactions labeled as...
متن کاملSkin test protocol for the prevention of hypersensitivity reactions to oxaliplatin.
BACKGROUND/AIM Several hypersensitivity reactions (HSRs) to oxaliplatin have been reported. Presently, there is no reliable way to predict the development of this adverse reaction. The aim of the present study was to evaluate the reliability of skin tests in the detection of patients at risk of developing HSRs to oxaliplatin. PATIENTS AND METHODS Patients under treatment with oxaliplatin unde...
متن کاملClinical Features of Oxaliplatin Induced Hypersensitivity Reactions and Therapeutic Approaches.
Oxaliplatin, a third generation novel platinum compound is the most effective first line chemotherapeutic agent for colorectal cancer (CRC) in combination with 5FU and leucovorin. It is indicated for pancreatic, gastric and testicular cancers combined with bevacuzimab, capecitabine, irinotecan and other cytotoxic agents. However, moderate to severe hypersensitivity reactions (HSR) during or aft...
متن کاملDiagnosis and management of hypersensitivity reactions caused by oxaliplatin.
Hypersensitivity reactions to oxaliplatin have been increasing since its introduction at the end of the 1990s, but allergy tests with antineoplastic drugs are rarely used to aid diagnosis. We describe 5 cases in which hypersensitivity reactions to oxaliplatin after several courses of chemotherapy were managed by allergy testing and desensitization. Skin prick tests were negative at 1 mg/mL in a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Value in Health
سال: 2010
ISSN: 1098-3015
DOI: 10.1016/s1098-3015(11)73104-7